General Information

  • ID:  hor001091
  • Uniprot ID:  NA
  • Protein name:  RFamide
  • Gene name:  NA
  • Organism:  Locusta migratoria
  • Family:  FMRFamide related peptide family
  • Source:  animal
  • Expression:  gut and/or from endocrine-like midgut cells
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  LWENLRF
  • Length:  7
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T7 Phenylalanine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Play a role in the regulation of digestion
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor001091_AF2.pdbhor001091_ESM.pdb

Physical Information

Mass: 108433 Formula: C47H68N12O11
Absent amino acids: ACDGHIKMPQSTVY Common amino acids: L
pI: 6.41 Basic residues: 1
Polar residues: 1 Hydrophobic residues: 4
Hydrophobicity: -28.57 Boman Index: -1322
Half-Life: 5.5 hour Half-Life Yeast: 3 min
Half-Life E.Coli: 2 min Aliphatic Index 111.43
Instability Index: 6991.43 Extinction Coefficient cystines: 5500
Absorbance 280nm: 916.67

Literature

  • PubMed ID:  17707763
  • Title:  Isolation and Sequencing of Two FMRFamide-related Peptides From the Gut of Locusta Migratoria L